Radioimmunterapi mot HER-2-positiv bryst- og eggstokkreft

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Probing DNA by 2-OG-Dependent Dioxygenase

TET-mediated 5-methyl cytosine (5mC) oxidation acts in epigenetic regulation, stem cell development, and cancer. Hu et al. now determine the crystal structure of the TET2 catalytic domain bound to DNA, shedding light on 5mC-DNA substrate recognition and the catalytic mechanism of 5mC oxidation.

متن کامل

Preclinical HER-2 Vaccines: From Rodent to Human HER-2

Effective prevention of human cancer with vaccines against viruses, such as HBV and HPV, raises the question whether also non-virus related tumors could be prevented with immunological means. Studies in HER-2-transgenic mice showed that powerful anti-HER-2 vaccines, could almost completely prevent the onset of mammary carcinoma. Protective immune responses were orchestrated by T cells and their...

متن کامل

Serum-albumin and risk of thyroid cancer: A population-based, matched case-control study

Flere epidemiologiske undersøkelser fra 1980og 1990-årene har funnet en invers assosiasjon mellom salbuminnivået og sykelighet/dødelighet av kreft. I utforskningen av skjoldkjertelkreftens etiologi og patogenese ble det derfor ansett som viktig å finne og bestemme styrken av en slik sammenheng når det gjelder skjoldkjertelkreft. Derfor ble alle med tilstrekkelig mengde serum deponert i Janusban...

متن کامل

Expression of heregulin, phosphorylated HER-2, HER-3 and HER-4 in HER-2 negative breast cancers.

A significant number of HER-2 amplified breast cancers is effectively treated by trastuzumab and further shows receptor-enhanced chemosensitivity. Recent studies have postulated transactivation of HER-2 also in tumors expressing phosphorylated/activated HER-2 (pHER-2) and of the HER-3/HER-4 ligand heregulin (HRG), independent of HER-2 amplification. As a consequence, a subset of tumors without ...

متن کامل

HER-3 expression in HER-2-amplified breast carcinoma

AIM OF THE STUDY To determine whether the expression of HER-3 influences the survival of HER-2 positive patients with breast cancer (BC). MATERIAL AND METHODS In the present work, the expression of HER-3 in a group of 35 HER-2 positive patients with BC was studied by performing immunohistochemistry (IHC) in formalin-fixed paraffin embedded tissues. RESULTS Higher HER-3 status if estimated b...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Tidsskrift for Den norske legeforening

سال: 2013

ISSN: 0029-2001

DOI: 10.4045/tidsskr.13.0503